Built for How Business Buys.
ESC4000-E11
2U dual-socket GPU server powered by 5th Gen Intel Xeon Scalable processors that supports four dual-slot GPUs, 16 DIMM, six NVMe, two 2600W Titanium power supplies and ASUS ASMB11-iKVM
KEY FEATURES
- Powerful performance: Powered by 5th Gen Intel® Xeon® Scalable processors unleash up to 21%-greater general-purpose performance per watt, significantly improving AI inference and training
- AI and HPC workloads ready: Up to four dual-slot active or passive GPUs, and NVIDIA NVLink® bridge support to enable performance scaling
- Power-efficient system design: Independent CPU and GPU airflow tunnels for thermal optimization and support for up to two 2600W Titanium redundant power supplies for uninterrupted operation
- Scale-up storage and expansion design: A total of six bays in combination of Tri-Mode NVMe/SATA/SAS drives on the front panel and 10 PCIe 5.0 slots for higher bandwidth and system upgrade
- Flexible networking module design: PCIe 5.0 slot in rear panel for faster connectivity
- Enhanced IT-infrastructure management: ASUS ASMB11-iKVM remote control with ASPEED AST2600, ASUS Control Center IT management software and hardware-level Root-of-Trust solution
Accelerate performance for HPC and AI workloads
Four dual-slot GPU compute in 2U
ESC4000-E11 is a dual-socket server powered by 5th Gen Intel Xeon Scalable processors and built for the demands of enterprise AI infrastructure to deliver unprecedented performance with industry-leading GPUs, faster GPU interconnect and higher-bandwidth fabric, and supports up to four dual-slot active or passive GPUs scalable configuration with a choice of NVIDIA NVLink® Bridge to enable scaling of performance with increased bandwidth — ready to match your AI and HPC workloads.
PCIe 5.0 Ready
Faster storage, graphics and networking capabilities
PCI Express® (PCIe®) 5.0 delivers 32 GT/s bandwidth, which is twice the speed of PCIe 4.0, and offers lower power consumption, better lane scalability and backwards compatibility. ASUS servers are PCIe 5.0 ready, with scalable designs to satisfy the increasing workloads or modern data centers.
System Layout
Panel Layout
Block Diagram
Sustainability
Keep your data center green
Data centers can consume huge amounts of electricity, raising environmental concerns. ASUS servers are designed to optimize both total cost of ownership (TCO) and total cost to the environment (TCE), including thermal design, power efficiency and advanced cooling solutions — reducing the impact of our products on the planet.
Optimized Thermal Design
Redundant Power
Management
Comprehensive IT infrastructure solutions
Advanced ASUS management tools comprise IT assets management, security and reliability to improve the performance, up-time and real-time monitoring of the servers remotely — highly increasing the efficiency of IT infrastructure.
BMC Management
ASUS Control Center
Platform Firmware Resiliency
TPM 2.0
Omniverse
NVIDIA® solutions for 3D collaboration
NVIDIA Omniverse partnership
NVIDIA is dedicated to its partners and believes that a strong partnership is the foundation of mutual success.
Full ASUS product lineup for Omniverse Enterprise
ASUS has the world’s best PCs, servers, monitors and graphics cards. With an expanding range of superior content-creation and gaming products, ASUS leads the industry through innovation to create the most ubiquitous, intelligent productivity.
Strong partnership with 3D partners
Connect to the top industry apps your teams use every day, with plug-ins that enable live-sync collaboration and iteration across multiple software suites simultaneously — all brought together in Omniverse Enterprise.
Success cases
Reduce deployment risks with a complete suite of VMware data-center products for Omniverse Enterprise.
Serviceability
Improved IT operational efficiency
Tool-less Cover
ASUS servers feature three easy-access covers that can be opened without tools, enabling IT staff to perform maintenance on specific components without removing the server fully from the rack.
Front-bezel Q-Code
ASUS servers have a visible Q-Code/port-80 LED display LED for simple monitoring of the entire boot process, from power on through loading of the operating system.
Hot-swap design
ASUS servers feature multiple hot-swap components, including fans, power supplies and storage for easy troubleshooting to keep 24/7 seamless operations.
Performance
5th Gen Intel® Xeon® Scalable Processors
5th Gen Intel® Xeon® processors unleashes up to 21% average general-purpose performance gain, significantly improving AI inference and training, all via the drop-in-compatible LGA-4677 socket. This innovation powerhouse accelerate AI, HPC, Analytics, Networking, Storage and offer eight DDR5-5600 memory channels for up to 2 TB capacity, 80 PCI Express® 5.0 lanes with CXL 1.1 support, and a 350 W TDP for 1P and 2P configurations — ready for the future of computing.
* Availability of accelerators varies depending on SKU.

























